REN Qi ② , LIU Lu, CHEN Wanyi

(Dept. of Neurology, the Fourth Affiliated Hospital of Guangzhou Medical University,Guangzhou 511300, China)

Abstract Objective: To investigate the status and risk factors of cognitive function recovery in patients with cevebral ischemic stroke (CIS) after thrombolytic therapy. Methods: A total of 80 CIS patients were selected, whose cognitive function recovery and the risk factors for abnormal cognitive function recovery of CIS patients after thrombolytic therapy were statistically analyzed. Results: Among 80 patients,11 patients (accounting for 13. 75 % ) had suffered from abnormal cognitive function recovery. Logistic regression analysis showed that older age, higher NIHSS score, time from onset to thrombolysis ≥4.5 h and metabolic syndrome were risk factors for abnormal cognitive function recovery in CIS patients after thrombolytic therapy (OR>1, P<0.05). Conclusion: The abnormal recovery of cognitive function in CIS patients after thrombolytic therapy is related to older age, higher NIHSS score, time from onset to thrombolysis ≥4.5 h, metabolic syndrome, and the like.

Keywords: cevebral ischemic stroke; thrombolysis; cognitive function; neurological deficits; metabolic syndrome

DOI:10.19296/ j.cnki.1008-2409.2023-01-021

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